Vitiligo is a common acquired pigment loss skin and mucous membrane disease, which can involve hair follicles and clinically manifest as white patches or (and) white hair. Vitiligo is examined by clinical manifestations, Wood’s lamp examination, skin imaging, histopathology, laboratory tests, and so on. 1. Clinical manifestations: any part of the body can be seen in the white spots, especially in the face, hands, wrists, etc., the white spots can be single, distributed or widespread, the typical lesions of milky white or porcelain white pigmentation, etc., the progress of the itchy stage can be. 2. Wood lamp examination: Vitiligo stable stage presents a bright blue-white fluorescence, border is clear, visible edge pigmentation or pigment islands, the progress of the skin lesions presented as gray-white fluorescence, border is not clear. 3. Skin imaging: complete loss of the pigment ring at the epidermis-dermis junction in the stable stage, with clear borders, and loss of the integrity of the pigment ring at the epidermis-dermis junction in the progressive stage, with highly refractive cells visible in the surrounding area. 4. histopathology: atypical vitiligo can rely on the histopathological examination of the lesions clear, typical white spots at the epidermal pigment granules and melanocytes are completely missing, the edge of the progressive lesions can be seen in the lymphocyte infiltration. 5. laboratory tests: clinical diagnosis of vitiligo patients can be further tested for anti-thyroglobulin antibodies (TGAb) and other related antibodies, for patients with autoimmune diseases or syndromes, the corresponding autoantibody test should be carried out. The most important thing to remember is that you should be able to get a good deal of money for the money you have spent on the money you have spent on the money you have spent on the money you have spent on the money.