A high WT1 expression three months after bone marrow transplantation means that there is a possibility of disease recurrence. 1. Bone marrow transplantation is a therapeutic method of replacing the diseased bone marrow with normal bone marrow by feeding it intravenously into patients with hematopoietic abnormality, immunodeficiency of hematologic malignancies (such as leukemia or myelodysplastic syndrome, etc.) and some other malignancies. 2.WT1 gene is an oncogene in human body, which has a certain role in tumorigenesis and can be widely expressed in leukemia.WT1 gene can be used as an important gene marker for detecting leukemia microscopic residual disease and predicting leukemia relapse. Therefore, high WT1 expression after bone marrow transplantation indicates the possibility of relapse. However, the WT1 index is for reference only. To determine whether the disease has relapsed, you must go to a regular hospital and be judged by a professional doctor, not blindly.