Costal neuralgia is more serious. It may be caused by degenerative herniation of thoracic intervertebral disc, tuberculosis of thoracic spine, fracture or dislocation of thoracic spine, tumor of spine or spinal cord, ankylosing spondylitis, etc. Clinical symptoms are that the pain will be aggravated when coughing or taking a deep breath, and it is mostly unilateral pain, but it can also occur bilaterally at the same time. The treatment of costal neuralgia should focus on the cause of costal neuralgia, according to the cause, you can choose to use ibuprofen, rofecoxib, celecoxib and other drugs for treatment, if the cause of the pain is a tumor, then it should be surgically removed at the earliest possible time. All of the above drugs should be used under the guidance of a professional doctor to avoid adverse reactions caused by self-medication.