There is no need to stop taking Polivir, i.e., clopidogrel bisulfate tablets, after one year of administration. Unauthorized discontinuation of medication increases the risk of cardiovascular events, and the medication should be used in accordance with medical advice. Clopidogrel bisulfate tablets are antithrombotic drugs, clinically used as secondary prevention of thrombotic events in acute coronary syndromes, recent myocardial infarction, recent ischemic stroke, and peripheral arterial disease. This drug if there is no obvious adverse reaction or the need for surgery, it is generally not recommended to stop, should follow the doctor’s instructions for long-term use of the drug, and there is no need to stop taking it after one year. It should be noted that the drug is prone to adverse reactions such as nosebleeds, gastrointestinal bleeding, abdominal pain, etc. The drug should not be used if there is active pathologic bleeding, severe liver damage, or allergy to the components of the drug. The use and adjustment of the drug should be carried out under the supervision of a doctor to avoid adverse consequences.