Depending on the cause of ankle pain, general treatment, medication, physical therapy and surgery should be carried out, which may be related to old injuries, rheumatoid arthritis, osteoarthritis and so on. 1. Old injury: there may be some old injury, such as ankle fracture, dislocation, etc., resulting in traumatic ankle arthritis, which leads to ankle pain in the early morning and walking for a while without pain. You can consider taking non-steroidal anti-inflammatory drugs such as Loxoprofen to relieve the discomfort. Physical therapy such as hot compresses and grilling can also be performed. If the indications for surgery are met, surgery such as ankle fusion can also be performed. 2. Rheumatoid arthritis: due to the abnormal immune response, resulting in multiple joint injuries, there will be stiffness and pain in the ankle joint when you wake up in the morning, but it will be relieved after moving around for a while. Some anti-inflammatory and anti-rheumatic drugs can be taken, such as diclofenac sodium and methotrexate. 3. Osteoarthritis: Osteoarthritis may occur due to the long-term overuse of the ankle joint, resulting in the wear and tear of the joint cartilage, which may cause stiffness and pain in the joints in the morning or when the joints are at rest. At this time, it is necessary to avoid weight bearing on the lower limbs of the affected side, and pain relieving drugs such as diclofenac sodium can be taken to relieve pain. Severe symptoms require surgical treatment, such as artificial joint replacement. There are other causes of ankle pain in the morning to walk for a while on the pain, such as lumbar disc herniation, etc., if the persistence of non-relief, it is recommended to seek medical attention in a timely manner, improve the examination to clarify the cause of the disease, comply with the doctor’s instructions to standardize the treatment, do not use their own medication, so as to avoid delays in the condition.