There is no such thing as “what medicine is effective for intestinal epithelial growth”. Intestinal epithelialization can be caused by Helicobacter pylori infection, chronic gastritis and other factors, need to be under the guidance of the doctor to carry out targeted treatment, such as drug treatment, general treatment, surgical treatment and so on. 1. Helicobacter pylori infection: usually adopt quadruple therapy, i.e. two antibiotics, a proton pump inhibitor and a bismuth agent, such as amoxicillin, metronidazole combined with omeprazole and bismuth potassium citrate. 2. Chronic gastritis: can be used to inhibit gastric acid secretion drugs, such as omeprazole, lansoprazole; gastric mucosal protective agents, such as Rebapatide, thioglycollate, etc.; accompanied by abdominal distension, nausea, and other symptoms of gastric motivation can be used to promote gastric drug therapy, such as doxepinone. If intestinal epithelial hyperplasia evolves into gastric cancer, surgery should be considered. Besides, one should maintain a light and easy-to-digest diet, eat small and frequent meals, avoid overeating and drinking, avoid alcohol and smoking, etc. Regular checkups will help early detection of gastric cancer. Patients diagnosed with intestinal epithelialization should actively cooperate with doctors for treatment. Medications should be used under the guidance of doctors.