Post-peritoneal dialysis peritonitis irritation of the intestine can cause diarrhea. When diarrhea occurs clinically, the patient can first be asked to observe whether the peritoneal dialysis fluid is clear, and if it is not observed with the naked eye, hospital examination is required. If the diarrhea is due to peritonitis, anti-coccus and anti-bacillus antibiotics can be added to the peritoneal dialysis fluid. After the results of bacterial culture are clarified, the antibiotics can be adjusted accordingly. If the diarrhea is not caused by peritonitis, the patient should be considered to have acute gastroenteritis or other conditions, and targeted medications for diarrhea should be administered, and gastroenterologists should be consulted if necessary.