In case of toothache, the symptoms of toothache can be temporarily relieved by taking painkillers such as oral ibuprofen and acetaminophen. The causes of toothache can be divided into odontogenic and non-odontogenic. Taking pain relieving drugs can only temporarily relieve the pain, but the real effective method needs to clarify the cause and treat the cause. It is recommended that patients should seek medical examination when they have toothache, and early treatment should be carried out to prevent aggravation of the condition and adverse consequences. I. Odontogenic pain: 1. General treatment: In addition to pain-relieving drugs, ice can be used to apply cold compresses and press acupuncture points such as Hegu, Shimonoseki and Buccal car to relieve symptoms; 2. Scaling treatment: Some patients may have toothache due to factors such as foreign body friction, and there may be calculus and plaque around the affected teeth, which can be removed by scaling the periodontal pathogenic factors, which can relieve pain to some extent; 3. Drug treatment If the toothache is caused by oral inflammation, such as periodontitis, pulpitis, etc., there is often fever, swelling, pus, etc., it can be treated by taking medication, the clinical use of chlorhexidine rinse, and oral amoxicillin, ibuprofen, metronidazole, etc., can effectively improve the symptoms of toothache. After the inflammation is eliminated, treatment will be carried out for dental pulp or periodontal disease; 4. Restoration and surgical treatment: if toothache is caused by caries, wedge-shaped defect and other serious damage to teeth, the caries part should be removed and filled and restored with resin and other materials; if toothache is caused by pulp disease and periapical inflammation, root canal treatment and crown should be worn. If it is accompanied by abscess, it also needs to be incised and drained; for the pain caused by obstructed teeth, the affected teeth can be extracted, which can effectively relieve the pain symptoms. Second, non-dental pain: non-dental toothache caused by neurological diseases and organ lesions, such as temporomandibular joint disorder, herpes zoster, trigeminal neuralgia, etc., is often accompanied by common symptoms of related primary lesions. Patients can take painkillers for temporary pain relief and actively treat the primary lesion to improve the symptoms of toothache.