Persons with tuberculous pleurisy have pain on deep breathing, which may be pleuritic chest pain produced by involvement of the pleura by the tuberculous lesion. Tuberculous pleurisy is caused by direct infection by Mycobacterium tuberculosis or its metabolites entering the pleural cavity and causing inflammation of the pleura, the exudate of which is cellulose with neutrophilic infiltration. In the early stage, the exuded cellulose adheres to the luminal surface of the pleura, and is pulled into a fluffy shape with respiratory movement, which may result in pins and needles chest pain, which may be aggravated with respiratory movement or coughing; in the later stage, with the increasing amount of exuded pleural effusion, the chest pain may be gradually relieved, but symptoms such as chest tightness and shortness of breath may occur. Patients suffering from tuberculous pleurisy need to be detected, diagnosed and treated early, and treated according to the principles of early, regular, whole course, appropriate amount and combined tuberculosis treatment.