Knee soreness after exercise may be due to strain, synovitis, osteoarthritis and other causes. It can be treated with general treatment, physical therapy, medication, surgery and other methods according to the cause. 1. Strain: Excessive exercise may cause strain on the muscles around the knee joint, resulting in knee soreness. At this time, you need to pay attention to rest, can be combined with hot compresses, massage and other methods of treatment, usually can be quickly relieved. 2. Synovitis: If the synovial membrane is damaged due to excessive exercise or too strenuous, it will cause synovial inflammation, which will also cause knee soreness and swelling. This time also need to pay attention to rest, can be in the acute period of cold compress, in the recovery period of hot compress. Non-steroidal anti-inflammatory and analgesic drugs, such as diclofenac sodium, can also be applied for treatment. Severe cases need surgical treatment, such as minimally invasive synovial cleaning. 3. Osteoarthritis: caused by degenerative joint disease, patients will have degenerative damage to the joint cartilage, which will also cause knee soreness after exercise. Usually pay attention to rest, avoid excessive exercise, you can also use diclofenac sodium and other treatment. It can also be treated with heat therapy and microwave. At the later stage of the disease, if deformity and activity obstacles occur, artificial joint replacement and other treatments are feasible. When there is soreness and swelling of the knee after exercise, if the symptoms can not be relieved, you can go to the hospital for further diagnosis and treatment. The above drugs need to be applied under the guidance of a physician, avoid self-medication.