When a person is severely mental or agitated and angry, the severity of the pituitary-adrenal system will rise, and the blood levels of catecholamines and cortisol hormones will increase and produce the following effects: 1. Catecholamines act directly on the heart, making the heart beat faster, the contraction force is strengthened, and the oxygen consumption of the heart muscle increases. When the coronary artery has been narrowed, it can cause increased myocardial ischemia and hypoxia, leading to angina pectoris and even myocardial infarction. 2, the action on the peripheral vasculature caused by small artery constriction, so that the peripheral resistance increases, blood pressure rises. Under the influence of repeated long-term mental severity factors, small arteries can continue to contract, resulting in degenerative thickening of the arterial wall, luminal narrowing, and a persistent increase in blood pressure. Both the intense constriction of small vessels and the catecholamines themselves can damage the vascular endothelium. The cholesterol in the blood can then take advantage of the situation and be deposited in the arterial wall, prompting atherosclerosis. 3, long-term serious can cause hyperlipidemia, while changing the hemodynamic state, making the blood thickening, platelets are also activated, releasing platelet pro-growth factor, prompting smooth muscle cells to proliferate, and easy to form thrombus. All these factors together contribute to the development of atherosclerosis. In addition, personality traits are also closely related to coronary heart disease. The Western Collaborative Group of the United States, through a survey, divided the personality into two types of A and B. Type A people are competitive, hostile, aggressive, lack of patience; type B personality is the lack of competition, and the opposite of type A. Through this comparison, it was found that the prevalence of coronary heart disease was higher in people with type A personality. It was also found in autopsies that arterial lesions were more pronounced in Type A personalities. Therefore, type A personality is also known as coronary heart disease susceptible personality, which is a more independent risk factor for coronary heart disease.