The survival period of patients with sigmoid colon cancer cannot be generalized, and it should be considered according to the staging of the tumor, treatment plan, patients’ own situation, etc. Generally speaking, the prognosis of early-stage patients after receiving regular treatment is good, while the prognosis of middle- and late-stage patients is poorer. Sigmoid colon cancer patients may not have obvious clinical manifestations in the early stage, which is easy to be neglected. With the development of the disease, abdominal pain, abdominal distension, blood in stool and other clinical manifestations often appear, and clinically, surgery is often used as the main treatment, supplemented with chemotherapy, and part of the early stage patients have a good prognosis after receiving regular treatment. The prognosis of some early-stage patients is relatively good after receiving regular treatment. The 5-year survival rate of early-stage colon cancer patients can reach 90%, while the prognosis of middle and late-stage patients is generally worse. It should be noted that sigmoid colon cancer patients can reduce the adverse effects of the disease through “early detection, early diagnosis and early treatment”, and many patients may survive for a long time, so it is recommended that patients establish confidence in treatment and actively fight against the disease.