Polypoid lesions of the gallbladder are generally not scary, but there is a risk of malignancy. Gallbladder polypoid lesions are a type of lesion that appears as a protrusion or bulge in the lumen of the gallbladder. The vast majority of patients are found on physical examination, usually without clinical symptoms and with good gallbladder function. A few patients may have right upper abdominal pain, nausea, vomiting, and loss of appetite. In asymptomatic patients, dietary adjustments can be made to minimize the intake of high cholesterol foods and greasy foods, and regular ultrasound examinations can be performed. If a single polyp larger than 1.0cm is found or there is a tendency of malignancy, timely surgical treatment, such as cholecystectomy. If malignant transformation occurs, it belongs to the category of more serious conditions, which is considered a terrible disease. In summary, gallbladder polypoid lesions are generally mild, but there is a risk of malignancy.