Bleeding on the second day of taking mifepristone is normal in most cases, but if heavy bleeding occurs, prompt medical attention is needed. Mifepristone is a clinical termination of pregnancy medication that can be used to medically abort intrauterine pregnancies up to 49 days old. After taking the drug, most people will experience a small amount of vaginal bleeding within a short period of time. However, it is important to note that if heavy bleeding occurs, you should go to the hospital immediately. Before the use of the drug, the clinician must be asked in detail to clarify that the duration of pregnancy is less than 49 days, and it must be clarified by ultrasound, etc. for intrauterine pregnancy before use; it is recommended to conduct a follow-up examination within 1-2 weeks after the use of the drug, to clarify the existence of incomplete abortion, continuation of the pregnancy, etc., and if there is the above situation, surgical intervention is required. Mifepristone is contraindicated in cases of unspecified intrauterine pregnancy, pregnancy longer than 49 days, drug allergy, cardiac, hepatic, renal and adrenocortical insufficiency, allergy to prostaglandin analogs, with intrauterine devices, suspected ectopic pregnancies, age older than 35 years, coagulation abnormalities, and hereditary porphyrias. The drug needs to be used under the supervision of a clinician.