Gallstone disease is currently the most significant biliary disease that harms our people, including liver and bile duct stones, gallbladder stones, and various complications caused by stones, with high incidence, complex conditions, and many complications. The pancreas is the second largest gland in the body and has both exocrine and endocrine functions. The exocrine secretion of the pancreas is pancreatic juice, which is a transparent liquid, mainly composed of various digestive enzymes (such as pancreatic protease, pancreatic lipase, pancreatic amylase, etc.), water and bicarbonate. The endocrine secretion of the pancreas comes from the islet cells in the pancreas, which mainly secrete insulin and hormones required by the body such as growth inhibitors. There are various risk factors for pancreatitis, with gallstone disease predominating in China, called biliary pancreatitis, while in the West it is mainly associated with excessive alcohol consumption. Biliary pancreatitis is caused by the common bile duct, which is the mouth of bile excretion, and the glandular opening of the pancreas, which has a common bile duct jug abdomen, and gallstones often lead to spasm or obstruction of the common bile duct, causing obstruction of pancreatic drainage. This leads to the activation of pancreatic zymogens, especially trypsinogen, which becomes a highly digestive enzyme, leading to self-digestion of the pancreas, thus causing pancreatitis. The clinical manifestations of biliary pancreatitis are pressure pain in the right upper abdomen or under the saber (heart fossa), abdominal distension, nausea and vomiting, fever, radiating pain or fasciculation in the shoulder and back, jaundice (yellowing of the sclera of the eyes and even the skin of the whole body), muscle tension in the upper abdomen, and positive Murphy’s sign; blood tests can reveal elevated blood levels, rising blood and urine amylase and blood lipase, and ultrasound and CT tests can further confirm the diagnosis. However, serum amylase rises after 8 hours of onset and continues to fall for 3-5 days. Therefore, serum amylase may be normal at the beginning of the disease, and sometimes it needs to be retested several times to be detected. Biliary pancreatitis mostly requires emergency surgery, and those who are critically ill and cannot tolerate surgery can have nasobiliary drainage and then undergo surgery when their general condition improves.