Fosamax generic name Polyethylene Glycol 4000 Bulk is usually taken to start a bowel movement within 24 hours to 48 hours, but this varies from person to person. Polyethylene Glycol 4000 Bulk is a medication with diarrhea-relieving properties, mainly made from a mixture of ethylene oxide and water polycondensation, and is suitable for the treatment of adults and children aged 8 years and above with constipation symptoms. The drug is generally effective within 24 to 48 hours after use, but because the severity of constipation of the user is different, the degree of absorption of the drug is not the same, so the actual time needed to defecate after the use of the drug also varies. Note that the drug should be contraindicated in people who are allergic to the product, people with confirmed or suspected intestinal obstruction, people with gastrointestinal perforation, people with inflammatory bowel disease, people with toxic megacolon, and people with abdominal pain without a clear diagnosis. Adverse drug reactions include abdominal pain, diarrhea, abdominal distension, nausea and so on. Specific medication should be administered under the guidance of a specialist, and should not be used without authorization.