It is normal for shingles to hurt badly for two days with medication. Herpes zoster is caused by the varicella-zoster virus and manifests itself in the form of erythema and blisters on the surface of the skin, accompanied by significant pain symptoms. The main symptom of herpes zoster is pain, is due to the virus so that the nerve inflammation or necrosis, thus causing neuralgia, the disease attack period, even after the use of medication, the inflammation subsides or the nerve repair also needs a certain process, usually will be in about 5 to 7 days, the pain will be relieved, the elderly pain lasts a little longer, so the herpes zoster medication two days of severe pain is normal. Patients with shingles should closely observe the changes in the rash. If the rash and pain disappear smoothly after treatment, there is no need for a follow-up, if the pain persists and recurs, it is recommended to go to the hospital in time.