Uric acid is a product of metabolism in the body and is produced by the breakdown of purines in the nucleus of cells. Under normal purine diet, fasting blood uric acid level is higher than 420mmol/L in men and 360mmol/L in women on two different days, which is called hyperuricemia. Obesity, diabetes mellitus, hypertension, hyperlipidemia and atherosclerosis are often associated with hyperuricemia, and affect and aggravate each other. The dangers of hyperuricemia 1, hyperuricemia and gout: hyperuricemia is the basis for the development of gout, although a mild or occasional increase in the value of uric acid in the blood will not cause gout, stones and arthritis. However, if it is too high for a long time, uric acid salts will deposit down at the cartilage and joints of the body and cause damage, then gouty arthritis and joint deformation will occur. The higher the blood uric acid level, the greater the possibility of gout in the next 5 years. 2. High uric acid stimulates the walls of blood vessels, promotes atherosclerosis and aggravates hypertension and coronary heart disease. Hyperuricemia can be one of the independent risk factors for coronary heart disease and cerebrovascular disease. 3, hyperuricemia and diabetes: long-term hyperuricemia can destroy the function of pancreatic beta cells and induce diabetes. 4, hyperuricemia and kidney damage: a large amount of uric acid passes through the renal tubules for a long time, forming uric acid crystals and stones deposited in the kidneys, causing gouty nephropathy, kidney function damage, and even uremia. Given that long-term hyperuricemia has many hazards to human health and life safety as mentioned above, patients must pay high attention to it. Basic treatment of hyperuricemia 1. Improve lifestyle: including healthy diet, quit smoking and alcohol, adhere to exercise and weight control. (1) Healthy diet: First of all, we should control the total caloric energy intake, and the diet should be based on low purine food, including cereals, vegetables (except those containing high purine such as spinach, lentils, beans, mushrooms, mushrooms, fresh peas, etc.), sugar, fruit juices, dairy, eggs, tea, dried fruits, red wine, etc.; appropriately control the z entry of coarse grains, meat, fish, shellfish, beans and their products; strictly control seafood, animal offal, thick gravy, anchovies, sardines and other food intake. (2) Drink more water, drink more than 2000ml of plain water daily to ensure that the urine volume is more than 1500ml to promote uric acid excretion; forbid drinking beer and liquor, because alcohol will reduce uric acid excretion, beer in particular. (3) Insist on exercise and weight control: daily moderate intensity exercise for more than 30 minutes. Obese people should lose weight, so that the weight control in the normal range. However, elevated blood uric acid caused by strenuous exercise or injury should be avoided. 2.Take soda tablets (sodium bicarbonate tablets) for a long time to alkalize urine, high solubility of uric acid in alkaline urine, 1-2 grams of soda tablets each time, 4 times a day. 3, after the above treatment, blood uric acid is still at a high level (500umolL); or uric acid is still higher than the upper limit of the normal index, and combined with obesity, diabetes, hypertension, hyperlipidemia and arteriosclerosis, as well as renal insufficiency, should be under the guidance of the doctor, according to medical advice, and regular re-examination.