Menopausal depression syndrome refers to a series of physical and psychological symptoms that occur during the perimenopausal period, that is, around the time of menopause, due to sudden fluctuations in the level of sex hormones secreted in the body. In addition to menstrual disorders, vasodilator disorders, hot flashes, sweating and other physiological symptoms, many women also experience psychological symptoms such as lack of concentration, mood swings, depression and inability to control themselves. 1.Appropriate psychological counselling: to enable perimenopausal women to understand that this stage is actually a normal physiological process, and should actively and actively adapt to it with a more optimistic attitude. 2.Establish a good lifestyle: insist on physical exercise, healthy diet, quit smoking, quit drinking, increase sunlight hours, and consume sufficient protein and calcium-rich food. 3.Establish a good lifestyle: insist on physical exercise, healthy diet, quit smoking, quit drinking, increase sunlight hours, and consume sufficient protein and calcium-rich food. Hormone supplementation: If there are clear indications and no contraindications, such as unexplained vaginal bleeding, breast cancer or other tumors, thrombotic diseases, liver and kidney dysfunction and other contraindications. 4. Antidepressant medication: Some menopausal depression will continue to develop and become more serious, obviously affecting daily life, so it is necessary to find a psychiatrist for diagnosis and evaluation and give antidepressant medication.