Panic caused by stomach discomfort is a reflexive symptom, which needs to be treated with drugs to inhibit gastric acid and protect gastric mucosa. The stomach and the heart are adjacent to each other, when the stomach occurs, it can reflexly cause symptoms of discomfort in the heart area; common gastric diseases include gastritis, gastric ulcer, etc., when the disease attacks, it will stimulate the nerves in the stomach, which will be manifested as gastric pain and bloating, and some of the patients can have symptoms of panic, and the discomfort in the stomach can reflexly cause the heart to beat faster, which will be manifested as the symptoms of heart panic. Patients who experience panic should pay attention to the electrocardiogram examination. If the cause is considered to be the digestive system, it is recommended to perform gastroenteroscopy examination to clarify whether the panic is caused by stomach diseases. Gastric disease caused by panic should be given to inhibit gastric acid to protect the gastric mucosa of the drug treatment, such as omeprazole, the specific use of medication should follow the doctor’s instructions, do not blindly use their own medication.