Patients with premature ejaculation can be cured by taking drugs such as Dapoxetine and Doxazosin as prescribed by the doctor, but some patients also need to be combined with psychotherapy and surgical treatment. Premature ejaculation is a common disease in men, because the disease will have an impact on physical and mental health, so patients can take dapoxetine, citalopram, paroxetine, sertraline and other 5 hydroxytryptamine reuptake inhibitors as prescribed, but also doxazosin, terazosin, alfuzosin and other alpha-adrenergic blockers as prescribed, which can help to improve the uncomfortable symptoms, the disease is cured. In addition to the above oral medication, can also be prescribed local injection of lidocaine, proparacaine and other local anesthetic drug treatment, and medical treatment for psychotherapy. For patients with unsatisfactory drug treatment and serious conditions, they can also seek medical treatment through surgical procedures such as dorsal penile nerve selective cutting. It is recommended that patients with premature ejaculation follow the doctor’s instructions to use medication, not to use drugs indiscriminately. Daily attention to maintain physical and mental pleasure, avoid bad sexual behavior, should also be appropriate physical exercise, to ensure a balanced intake of nutrients and so on.