The male deltoid region distension pain may exist pelvic floor muscle tension, prostatitis, as well as testicular, spermatic cord disease, it is recommended to go to the hospital for further examination, to take the appropriate drug treatment. 1. If long-term sedentary, tired, mental stress, as well as drinking, staying up late and other bad habits may cause muscle tension in the pelvic floor muscles, swelling and pain in the deltoid region, it is recommended to avoid sitting for a long time, regular work and rest, and more exercise can be effective in relieving the pain. 2. If prostatitis exists, acute bacterial prostatitis is recommended to be treated with intravenous penicillin and other broad-spectrum antibiotics; chronic bacterial prostatitis can be treated with oral levofloxacin, tamsulosin hydrochloride and other medications according to the drug sensitivity of a few choices; in addition to the recommendation to exercise, avoid sedentary activities, refrain from alcohol, and have a regular work and rest. 3. If there is testicular syringomyelia, varicocele, etc., it is recommended to choose indomethacin and other drugs according to the severity of the disease, as well as surgical treatment, such as spermatic vein ligation. Therefore, it is recommended to go to the hospital in time for further examination and treatment under the doctor’s guidance. The application of the above drugs should be under the guidance of a specialized physician.