Liver area pain when pressed and no pain when not pressed may be due to trauma, cholecystitis, acute hepatitis, and should be taken seriously and treated actively. 1. Trauma: when the patient’s right upper abdomen is squeezed or collided, it will lead to local soft tissue injury, which will cause the patient to have the symptom of pain in the liver area when pressed but not when pressed. 2. cholecystitis: the pain in the liver area may be due to cholecystitis, cholecystitis patients will have pain in the right upper abdomen, some patients will also have vomiting, nausea and other symptoms, accompanied by fever. 3. Acute hepatitis: Acute hepatitis can lead to nausea, vomiting, low-grade fever, yellow urine, anorexia and other symptoms. At the same time, it will cause the patient to have pain when pressing the liver area. Appearance of pain in the liver area by pressing not pressing, no pain may also be due to gallstones or liver tumors, it is recommended that patients should seek medical examination in time to avoid delaying the condition.