High tumor markers in lung nodules may be caused by inflammatory infection, and it is not excluded that it is caused by early lung cancer. 1. Inflammatory infections: when there are inflammatory infections in the lungs, it may cause lung nodules, and if they are benign lung nodules, high tumor markers may also appear when doing examination. 2. Early stage lung cancer: when there is malignant tumor in the body, such as early stage lung cancer, there will be nodules in the lungs accompanied by high tumor marker when doing examination. Lung nodules with high tumor marker need to go to the hospital regularly to do chest CT examination, and if necessary, they need to do puncture biopsy to send pathological tests to determine the severity of the disease, and then targeted treatment.