The main treatments for interstitial pneumonia over 10 years include improving the respiratory environment, medication such as glucocorticoids, lung transplantation, and other treatments. Interstitial pneumonia can be simply divided into secondary and idiopathic according to the presence or absence of a clear cause. In the case of secondary interstitial pneumonia, it is necessary to actively deal with the primary disease, while idiopathic interstitial pneumonia does not have a clear cause and the prognosis varies greatly, with a small number of patients with a disease duration of up to 10 years or more. 1. Active treatment of the primary disease: if the disease is caused by connective tissue disease, it is necessary to actively treat the primary disease. 2. Drug therapy: glucocorticosteroids, such as prednisone, have a very good anti-inflammatory effect, which can reduce the inflammatory reaction of the pneumonia attack, and can also be used in combination with immunosuppressants, such as cyclophosphamide, and antifibrotic drugs, such as pirfenidone, pay attention to the use of drugs must follow the doctor’s instructions. 3. Surgery: Lung transplantation is the most effective treatment for patients with respiratory failure and severe fibrosis of the lungs at the end stage. 4. Other treatments: Pneumonia and influenza vaccination to strengthen the body’s immunity can reduce the risk of infection during the disease season; in addition, oxygen or clinical mechanical ventilation to correct hypoxia and improve the quality of life. For patients with interstitial pneumonia who have had the disease for many years, it is important to pay attention to nutritional supplements in daily diet and do some pulmonary function rehabilitation exercises appropriately, and if the disease worsens or has a tendency to deteriorate, it is important to consult a doctor as soon as possible.