The first thing you need to do is to get rid of the sting, and then wash the sting with soap and water repeatedly. 2. 3. Oral medication: If the local redness and swelling is strong, you can take oral anti-allergy medication, such as levocetirizine hydrochloride and loratadine. If the pain is also obvious, you can take non-steroidal anti-inflammatory drugs for pain management, such as ibuprofen. 4. Go to the hospital: If the redness and swelling is particularly strong, you sometimes need to go to the dermatology department of a regular hospital to use drugs for treatment under the guidance of a specialist, and to see if antibiotics are needed at the specialist’s discretion. After a hornet sting, some patients may experience redness and swelling, while others may experience allergic symptoms such as chest tightness, difficulty breathing, or even shock, which may require a visit to a regular hospital.