There are five categories of antihypertensive drugs: diuretics, beta-blockers, calcium antagonists, angiotensin-converting enzyme inhibitors (ACEIs), and angiotensin II receptor antagonists (ARBs), which are to be selected individually according to the patient. 1. Diuretics: e.g. hydrochlorothiazide, aminopterin. It is suitable for mild and moderate hypertension, and has strong antihypertensive effect on simple systolic hypertension, salt-sensitive hypertension, obesity, diabetes, menopausal women, heart failure and the elderly. It is contraindicated in gout. Potassium-preserving diuretics should not be combined with ACEI and ARB, and should be used with caution in renal insufficiency. 2. β-blockers: such as propranolol, metoprolol. It is suitable for middle-aged and young people with fast heart rate or those with angina pectoris and chronic heart failure, and should not be stopped suddenly when treated with high doses. Acute heart failure, sick sinus node syndrome, atrioventricular block is prohibited. 3. Calcium antagonists: such as nifedipine, verapamil. For the elderly, high sodium intake, taking non-steroidal anti-inflammatory drugs, alcoholism, diabetes, coronary heart disease or peripheral vascular disease patients, long-term treatment can be anti-atherosclerosis. Non-dihydropyridines are not suitable for patients with heart failure, sinus node hypoplasia or heart block. 4. ACEI: such as captopril, enalapril, suitable for obesity, diabetes, heart failure or renal function is not good patients, should monitor the blood creatinine and blood potassium. Hyperkalemia, pregnant women and bilateral renal artery stenosis is contraindicated. If adverse reactions such as irritating dry cough is excessive, it can be replaced with ARBs such as chlorosartan and valsartan, with the same contraindications as ACEI. Hypertension is not only treated by medication, but also by improving lifestyle while actively intervening in coexisting cardiovascular disease.