Twelve-year-old girls with armpit odor may be due to have entered the developmental stage of puberty, sweat glands gradually developed and mature, can be improved by improving lifestyle habits, medication and other methods to alleviate the symptoms. If the symptoms of armpit odor are mild, it is recommended to pay attention to cleanliness and hygiene in daily life, bathing, changing clothes, try to keep the armpits clean and dry, if there is armpit hair, you can shave the armpit hair to reduce the number of bacteria, so as to achieve the purpose of alleviating armpit odor, usually wash the armpits can be coated with some antiperspirant spray or antiperspirant to alleviate the phenomenon of sweaty armpits. If the twelve-year-old girl has armpit odor symptoms are more serious, you can follow the doctor’s instructions to use aluminum chloride solution, povidone iodine solution and other drugs to relieve, but also through the botulinum toxin local injection to reduce the activity of the nerve sweat glands, so as to achieve the purpose of treatment. Patients with severe symptoms can also consider physical therapy such as gold microneedle or fresh microwave after adulthood, using light and heat utility to destroy sweat gland tissues and alleviate symptoms, or surgical treatment such as removal of axillary sweat glands. Twelve-year-old girl with armpit odor is recommended to go to the hospital in a timely manner, after a clear diagnosis according to the doctor’s guidance for standardized treatment.