Chinese medicine treatment of premature ejaculation requires evidence-based treatment, which can be divided into the evidence of damp-heat in the liver meridian (the liver meridian feels damp-heat evil qi), the evidence of deficiency in the heart and spleen (the heart and spleen are weak), the evidence of phase fire, and the evidence of renal qi not being solid. 1. Clinical manifestations of Liver Meridian Damp-Heat syndrome are easy to lift the penis, premature ejaculation, accompanied by chest tightness and dystocia (pain in the area of coercion and ribs), bitter taste in the mouth and dryness in the throat, yellowish and turbid urine, and wet and itchy scrotum. The representative formula is Longdian Diarrhea Liver Tang. 2. Clinical manifestations of deficiency of heart and spleen include premature ejaculation, forgetfulness and dreaminess, palpitation (rapid heartbeat, often accompanied by panic), palpitation (violent heartbeat, panic), abdominal distension and loose stools (scanty and unformed stools), scanty appetite, and fatigue (mental fatigue and physical weakness). The representative formula is Gui Spleen Tang. 3. Clinical manifestations of Phase Fire Paranoia include easy lifting of yang affairs, premature ejaculation, five heartburns and heat (heat in the hearts of the hands and feet, and self-consciousness of the heart and chest), soreness and weakness of the waist and knees (feeling of soreness and weakness of the waist and knees), hot flashes (a burst of heat), night sweating (abnormal sweating after going to sleep, and stopping of sweating after waking up). Representative formula is Zhi Bai Di Huang Wan. 4. Clinical manifestations of Kidney qi failure include premature ejaculation, loss of libido, spermatorrhea, clear urine, lumbar and knee soreness (a feeling of soreness and weakness in the lumbar and knee regions), and prolonged nocturnal urination. The representative formula is Jin Gui Ren Qi Wan. If premature ejaculation occurs, you should consult a doctor and use the prescription under the doctor’s guidance.