Slightly elevated human chorionic gonadotropin in the 50s is probably normal and is associated with decreased luteal levels and elevated luteinizing hormone, as well as with certain diseases. 1. Normal: Human chorionic gonadotropin is mainly secreted by placental trophoblast cells, and its main role is to stimulate luteinizing hormone and estrogen secretion. Luteinizing hormone is the hormone that stimulates ovulation and promotes estrogen secretion. The age of 50 is in the menopause stage, the luteal function declines at this stage, the pituitary gland to ensure that the luteal secretion level in the body so compensatory increase in luteinizing hormone, which leads to human chorionic gonadotropin rise. 2. Disease factors: hyperthyroidism, pituitary disease and other endocrine diseases and uterine cancer, gestational trophoblastic diseases may also lead to elevated human chorionic gonadotropin. Slightly elevated human chorionic gonadotropin in the 50s suggests that the patient undergo further examination to clarify the diagnosis and prevent missed or misdiagnosis.