Aminotransferases are a class of enzymes that catalyze the transfer of amino acids to and from keto acids. They are commonly found in animal tissues such as heart muscle, brain, liver and kidney. There are many types, among which glutaminase and glutamic aminotransferase are the most important. The former catalyzes the transamination between glutamate and pyruvate, and the latter catalyzes the transamination between glutamate and oxaloacetate. Glutathione is found mainly in liver tissues, while glutathione is found in the heart and other tissues and organs. Aminotransferase levels between 0 and 40 are normal. If it is outside the normal range, after excluding the possibility of errors due to factors such as malfunctioning laboratory equipment and operating errors, if the transaminase level is still high, it is most likely due to viral hepatitis or other liver disease. However, to determine whether it is viral hepatitis, other tests need to be done and a comprehensive analysis combined with medical history, symptoms and signs is needed. The common causes of elevated transaminases are as follows: 1. Diseases of the liver itself, especially viral hepatitis of various types, cirrhosis, liver abscess, liver tuberculosis, liver cancer, fatty liver, hepatomegaly, etc., can cause different degrees of elevated transaminases. In addition to liver, other organ tissues in the body also contain this enzyme, so when myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, type B encephalitis, polymyositis, acute septicemia, enteric typhoid fever, rheumatoid fever, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, extrusion syndrome, etc., the blood transaminases can also be seen to rise. Because transaminases are excreted from bile ducts, if there are bile duct, gallbladder and pancreatic disorders and bile duct obstruction, transaminases may also be elevated. 4.Pharmacogenic or toxic liver damage, as well as drug allergy can cause elevated transaminases, and are often accompanied by bilious jaundice and liver cell damage. In addition, aminotransferase levels in healthy people may also temporarily exceed the normal range. Strenuous exercise, overexertion, or eating fatty foods may cause a temporary increase in aminotransferases. If you worked late or did not sleep well the night before the aminotransferase test, or if you ate something fried for breakfast before the test, the test results may be outside the normal range.