I. Early and clear diagnosis and timely and correct treatment Because SLE is a variety of autoantibodies acting on multiple systems and organs, the clinical manifestations are diverse and often lead to misdiagnosis. In the early stage, it is easily misdiagnosed as rheumatism, rheumatoid arthritis, chronic nephritis, nephrotic syndrome, tuberculous pleurisy, hemolytic anemia, thrombocytopenic purpura, pericarditis, myocarditis, psychosis, epilepsy, skin disease, etc. In some cases, patients are examined by multiple hospitals before the diagnosis is confirmed. The reason for misdiagnosis is that doctors do not know enough about the characteristics of multi-system and multi-organ damage of the disease, and only grasp the clinical manifestations of one organ without in-depth understanding of medical history and detailed physical examination, thus making one-sided diagnosis. Especially in the early stage, most patients only have fever and joint pain as their first symptoms, so there are more misdiagnosis of rheumatism and rheumatoid rheumatism. In order to make early diagnosis, doctors should be highly alert to this disease, be familiar with clinical manifestations, and do corresponding examinations to realize the possibility of lupus erythematosus as soon as possible after the onset of the disease. ana is the best indicator for screening systemic lupus erythematosus, and almost all patients with lupus erythematosus have positive ana and high titer; anti-double-stranded dna antibody and anti-sm antibody are highly specific for lupus erythematosus diagnosis. Early diagnosis is a prerequisite for early treatment. For mild patients with only low fever, malaise, pleurisy and rash, oral NSAIDs such as anti-inflammatory pain and fenbid can be used as adjuvant treatment; glucocorticoids and other immunosuppressive drugs are applied to severe patients. Regular follow-ups are conducted on a regular basis, with comprehensive examinations every 1-2 months, and the dosage of medication is adjusted according to changes in the condition. When the disease is in remission, hormones can be gradually reduced or stopped. Chinese medicine has an important role in promoting and maintaining remission, reducing the side effects of hormones, regulating the body’s immune function, and preventing infection. Second, avoid triggering factors. The common triggering factors are: 1. sun exposure and ultraviolet radiation. In people with lupus quality, sunlight or ultraviolet irradiation changes intracellular deoxyribonucleic acid and generates antigenic antibody reactions, prompting lupus attacks. Multiple massive X-ray irradiation or strong electric light irradiation can lead to recurrence of the disease. Some limited discoid lupus erythematosus can become systemic lupus erythematosus or evolve from the chronic to the acute form after exposure to sunlight or irradiation. Therefore, patients with lupus erythematosus should avoid sun exposure, and when it is really difficult to avoid, they should use umbrellas, or wear broad-brimmed hats, long-sleeved clothes and pants, and apply sunscreen on their skin, such as 15% para-amino benzoic acid ointment, etc. 2. Cold stimulation. Lupus patients are most likely to suffer from cold. Cold stimulation can lead to recurrence of the disease, so add or remove clothes at any time when the climate changes or the seasons change, and wear hats and gloves when going out in winter to prevent getting cold. 3. Drug-induced. Some lupus patients develop the disease obviously related to drugs, such as penicillin, sulfonamides, bactrim, hydrazinpyridazine, procainamide, chlorpromazine, phenytoin sodium, isoniazid, oral contraceptives, etc., which can make lupus patients in remission enter the active phase and laboratory changes. 4. Pregnancy and childbirth. SLE occurs in women of childbearing age, and their fertility is the same as normal people. However, patients must be cautious when they become pregnant. This is because SLE and pregnancy have mutual adverse effects. The incidence of fetal abnormalities in pregnancy is higher in patients with SLE than in the normal population. Miscarriage can occur in the first trimester of pregnancy, especially in patients with active lupus nephritis, with 50% of pregnant women having miscarriage and about 2/3 of pregnant women having preterm delivery or stillbirth. Conversely, pregnancy also has a significant impact on lupus erythematosus, with more than half of patients experiencing an exacerbation or relapse of the disease in the last trimester of pregnancy and in the months following delivery. Pregnant women with lupus in remission are less likely to have a relapse, while pregnant women with active lupus have a much higher rate of disease progression than those in remission. The most serious effect of pregnancy on SLE is kidney damage. Therefore, married women in the reproductive stage must be guided by specialists as to whether they can get pregnant, when they can get pregnant, what problems they should pay attention to after pregnancy, and what contraceptive measures they should take if they cannot get pregnant. The remission and relapse of SLE are two opposing aspects, and the opposing sides can be transformed into each other under certain conditions. We can look for, capture and create favorable factors for remission and avoid or eliminate unfavorable factors for relapse. Catching early signs of relapse, early medication and self-protection, and putting out the “fire” without waiting for it to burn. Regular immunologic testing is essential, and patients in remission can be tested for ANA and anti-DNA antibodies every six months to a year if possible. If treatment is given at this time, the disease can be controlled so that it does not recur or can be treated promptly even if it does. Patients who are not in a position to undergo regular immunological examinations can estimate the possibility of relapse by self-perception, and if the original symptoms such as arthralgia, fever, malaise, etc. reappear, they should consult the doctor early and undergo necessary examinations, and take timely measures if there is activity. Psychological treatment and encouraging patients to build up confidence to overcome the disease Psychological treatment is an important part of the treatment of SLE. Patients with lupus erythematosus commonly have hair loss and facial rash, plus side effects produced by long-term use of glucocorticoids, such as obesity, full-moon face, buffalo back and other changes in appearance; long-term disease torture has a great impact on patients’ thoughts and emotions. Young women feel ashamed to see others, have a heavy burden of thought, and even have pessimistic and anorexic feelings. Long-term psychological imbalance is very detrimental to the treatment of the disease. It is very important to maintain a good mood when you are sick, and it can even play a role that drugs cannot play. Maintaining an optimistic mood, the mental immune function is active, the body’s ability to resist disease is strong, recovery is fast; on the contrary, emotional tension, anxiety, the immune system is low, the internal anti-disease function is not fully mobilized, the disease lingering recovery is slow. Psychological tension or bad emotion can trigger the recurrence of lupus erythematosus. Therefore, keeping a good emotional state and maintaining the relative stability of immune function is an important guarantee to avoid recurrence and early recovery. Doctors play a leading role in the psychological treatment of lupus erythematosus. First of all, a good doctor-patient relationship should be established, and the doctor should become a friend of the patient so that the patient will open his heart, which is conducive to finding the knot of the patient’s mind. Help patients to establish confidence in overcoming the disease, strengthen their strong will to overcome the disease, mobilize their subjective initiative, and exclude all kinds of negative factors; guide patients to cultivate a wide range of interests in life, cultivate sentiment, find the joy of life in various cultural and sports activities, let the joyful mood occupy the mental life space, and maximize the mobilization of immune mechanism of anti-disease effectiveness; guide patients to cultivate a resilient character, bravely face reality, and deal with the unexpected events in life. The patient should be instructed to cultivate a resilient character, face reality bravely, and deal with the unexpected events in life, etc., all of which are indispensable elements in psychotherapy.