The sequelae of alcoholism include damage to liver function, damage to the nervous system and changes in mental state, alcohol dependence and withdrawal syndrome. 1. Impairment of liver function: due to the prolonged stimulation of alcohol, patients will have cirrhosis of the liver, such as ascites and upper gastrointestinal bleeding; in addition, edema, proteinuria and hypertension will also occur. 2. Nervous system damage: due to the inhibition of nervous system function, patients will show symptoms such as somatic disorder and limb spasm. 3. Changes in mental state: as alcoholism will stimulate the increase of cortical electrical excitation, so the patients will have delirium, paranoia and confusion and other symptoms; severe cases may have memory loss and toxic hallucinations. 4. Alcohol Dependence and Withdrawal Syndrome: Due to long-term drinking or excessive intake of alcohol, it will lead to extreme craving for alcohol and characteristic seeking behavior during the early withdrawal period. The after-effects of alcoholism and its harmful effects on the body are greater, so the patient should quit drinking as soon as possible and undergo regular health checkups of all body systems.