Leg pain is associated with heart disease because of the heart’s ability to connect to vital blood vessels and tissues in the body, and because the thigh has the largest arterial system, leg pain can be caused by problems such as heart pressure and inadequate blood supply to the heart. In addition to leg pain, heart problems may also cause localized blood vessel spasms and thigh twitches, and it is important to take timely preventive efforts and psychological preparations to prevent heart disease from causing severe physical discomfort and reactions that can jeopardize the healthy development of the heart and mind and body, and it is normal for heart disease to cause leg pain. For patients it is necessary to take good care of the legs and promote blood circulation throughout the body. Leg pain caused by heart disease should also be treated and cared for in a timely manner in order to promote the ability of the thighs and lower legs to support the heart while alleviating various clinically uncomfortable reactions, and in order to cope with the signs of a heart attack, patients must also take emergency medication.