1, progressive vitiligo: (1) common type: Yang Ji, Department of Dermatology, Zhongshan Hospital, Fudan University ① limited type: can be topical glucocorticoids (referred to as hormones) or calcium-regulated neurophosphatase inhibitors (tacrolimus, pimecrolimus), etc., can also be topical low concentration of photosensitizing drugs; local phototherapy optional narrow-spectrum medium-wave ultraviolet (nb-uvb), 308nm excimer laser and excimer light, etc.
②Disseminated, pancytopenia and extremity type: phototherapy and topical drug treatment can be referred to the progressive limited type. In severe cases, systemic glucocorticoids can be considered. In addition, Chinese herbal medicine and immunomodulatory treatment are also important tools.
(2) Segmental type: refer to the progressive limited type treatment.
2, stable vitiligo: (1) common type: ①limited type: topical photosensitizers (8-MOP, etc.), hormones, calcium-regulated neurophosphatase inhibitors, vitamin D3 derivatives, etc.; autologous epidermal transplantation and melanocyte transplantation; local phototherapy refer to progressive limited type or photochemotherapy.
②Disseminated, pancytopenic and limbic types: phototherapy or photochemotherapy, such as NB-UVB, PUVA, etc.; Chinese herbal medicine; autologous epidermal transplantation or melanocyte transplantation (exposed site or site requested by the patient). Topical topical drug treatment is referred to the stable stage limited type.
(2) Segmental type: autologous epidermal transplantation or melanocyte transplantation, including autologous epidermal slice transplantation, microdermal slice transplantation, bladed thick skin slice transplantation, autologous non-cultured epidermal cell suspension transplantation, autologous cultured melanocyte transplantation. Other reference to stable stage limited treatment.
3.Other auxiliary treatment methods: Avoid sun exposure, trauma, stress, exposure to chemical depigmentation agents, etc. If necessary, use masking agents on exposed areas; supplement with vitamin B, vitamin E, etc.