Taking colloidal bismuth pectin or heartburn is considered to be related to medication irregularities, poor diet, insufficient course of treatment, and mismatch between the type of medication and the disease being treated. 1. medication irregularities: colloidal pectin bismuth is generally recommended to be taken one hour before meals or at bedtime, if the method of medication is not correct or not standardized to follow the doctor’s instructions for regular, quantitative medication and other circumstances will cause the drug does not achieve the therapeutic effect, or the symptoms of heartburn. 2. Poor diet: daily life often eat some high-fat food, chocolate, coffee, strong tea and so on can cause heartburn intensified, if only simple medication, do not actively control the diet will also cause heartburn. 3. Insufficient course of treatment: colloidal bismuth pectin is used in the combined treatment of Helicobacter pylori generally need to be taken for two weeks, and if you only take a day or two may not have significant symptomatic relief. 4. The type of drug does not match with the treatment of disease: for example, cardia dystrophy and other diseases, these diseases caused by heartburn symptoms with colloidal pectin bismuth can not be well relieved, can consider the use of nifedipine, omeprazole and other drug therapy, endoscopic or surgical treatment is not effective in internal medicine. After taking colloidal pectin bismuth or heartburn after standardizing the use of drugs, adjusting the diet and other methods can not be relieved, it is recommended to go to the hospital for medical treatment.