The course of treatment for H. pylori quadruple medication is usually 14 days, and the total cost is around $500, and the cost varies depending on the medication chosen. The quadruple combination of drugs for H. pylori mainly includes a proton pump inhibitor, two antibiotics, and a bismuth agent. Proton pump inhibitors can use omeprazole, lansoprazole and so on. Antibiotics are more commonly used such as amoxicillin, clarithromycin, and metronidazole. Bismuth agents may use bismuth potassium citrate. The treatment course is usually 10~14 days, and the cost is about 500 yuan, the cost of different drugs is different, you can consult a professional physician. The above drugs should be used under the guidance of professional physicians. The use of Helicobacter pylori quadruple drugs must be a full course of treatment, and review is recommended after treatment to observe the eradication of Helicobacter pylori.