Itchy skin on the legs in winter needs to be treated according to the cause, and common causes include dry skin syndrome and ichthyosis. It is usually treated with medication, including topical and oral medication. 1. Dry skin syndrome: due to the dry and cold climate in winter, the sebum secretion will be reduced, unable to form a sebaceous membrane, unable to moisturize the skin and prevent water loss, thus triggering dry skin syndrome, manifested as dry skin, roughness, chaffy flaking, accompanied by itching symptoms. Topical moisturizing agents, such as urea cream, vitamin E cream, etc., can be used topically. If the itching symptoms are severe, oral medications, such as loratadine tablets, chlorpheniramine maleate, etc., can be applied at the same time. 2. Ichthyosis: Ichthyosis is mostly caused by heredity, manifesting as dry, flaky and ichthyosiform lesions on the surface of the skin, which may be accompanied by mild itching, and the symptoms usually worsen or become more obvious in winter. Local topical moisturizing preparations, such as petroleum jelly and vitamin E cream, can be used. In severe cases, oral retinoids, such as Avitamin A capsules, can be taken at the same time. All of the above drugs have adverse reactions and are recommended to be used under medical supervision. Itchy legs in winter may also have other causes, it is recommended to go to the hospital in time to improve the examination, to clarify the cause of the disease to give targeted treatment.