Clindamycin phosphate gel is not recommended for the treatment of acne alone and is recommended to be used in combination with benzoyl peroxide or topical retinoids. If used in combination, the duration of use of Clindamycin Phosphate Gel needs to be determined by the condition. Clindamycin phosphate gel belongs to the antibiotic class of drugs, topical antibiotics are easy to induce resistance to Propionibacterium acnes, so it is not recommended to be used alone, need to be used in combination with benzoyl peroxide or topical retinoids. When clindamycin phosphate gel is used in combination with benzoyl peroxide or topical retinoids, the duration of use is determined by the patient’s condition, and in more severe cases, the duration of use is longer, and systemic treatment with oral medications is usually required to relieve acne symptoms. Clindamycin phosphate gel should be noted before use, should not be used for skin breakage, use to avoid contact with eyes and other mucous membrane parts, such as the mouth, nose and so on. In the process of use, the skin at the site of application may appear irritation, such as redness, swelling, itching, burning sensation, etc., it is recommended that the use of under the guidance of a doctor.