There is no clear information about how long the patients can live after surgery for advanced colon cancer with lymph node metastasis. Generally speaking, the five-year survival rate of patients is less than 20%, so patients should keep a good mindset and improve their diet and living habits to improve the quality of life. Patients with advanced colon cancer and lymph node metastasis have relatively poor prognosis after surgery, and their five-year survival rate is less than 20%, so it is suggested that patients should closely observe their condition after surgery. It is suggested that patients with advanced colon cancer with lymph node metastasis should keep a good and optimistic mindset to face the disease after surgery and avoid exertion. Patients should adjust their diet and eat less spicy and indigestible food, such as chili peppers, beans, yams and so on. Patients should ensure sufficient rest and avoid staying up late. The life expectancy of patients with advanced colon cancer and lymph node metastasis cannot be accurately judged after surgery, patients should develop healthy living habits, improve diet, take medication as prescribed by doctors and have a review after surgery.