Acne is usually referred to as acne and can be treated with topical medications such as retinoid creams, benzoyl peroxide gel, and antibiotic creams. Acne is related to genetic factors, increased sebaceous gland secretions due to androgen induction, hyperkeratosis of hair follicles and over proliferation of Propionibacterium acnes. 1. Vitamin A creams: common medications such as adapalene gel and vitamin A cream can promote epidermal cell renewal, thereby loosening and shedding keratinocytes, and are clinically applicable to common acne and keratosis pilaris. Common adverse reactions include contact dermatitis, itching, flaking, hyperpigmentation, erythema and so on. Allergic to the drug is prohibited, acute subacute dermatitis, eczema skin disease patients are prohibited, pregnancy and women planning to pregnancy, etc. Prohibited. 2. Benzoyl peroxide gel: the drug is a kind of oxidizing agent, used externally on the skin, can slowly release ecological oxygen and play a bactericidal effect, and at the same time and make the skin dry and flaky effect. Adverse reactions include contact dermatitis, burning sensation of the skin, itching, redness, dry and flaky skin. Allergic to the drug is prohibited; acute inflammatory skin disease patients, skin ulcers are prohibited. 3. Antibiotic creams: common such as fusidic acid cream, can inhibit the synthesis of bacterial proteins, so that protein synthesis stagnation, to play the role of bacterial inhibition, in high concentrations have a bactericidal effect. Clinically, it is mainly used to treat skin diseases caused by staphylococcus, streptococcus, Propionibacterium acnes and other sensitive bacterial infections, such as folliculitis, acne, boils and so on. Adverse reactions include rash, irritation, pain, and rashes. It is contraindicated for those who are allergic to the drug. There are many types of topical creams for acne, all of which need to be applied under the supervision of a doctor, and in severe cases, a combination of oral medication or physical therapy is also required. Acne may also be caused by other diseases, such as folliculitis, pityriasis rosea, facial disseminated milia lupus, etc. It is recommended that patients with acne go to a regular hospital in time to get a clear diagnosis, and standardized treatment under the guidance of the doctor.