Wounds may occur when scratched or bitten by animals, and the extent to which a wound requires rabies vaccination is closely related to the degree of wound damage and the health of the animal that caused the patient’s injury. A preliminary determination of whether a wound requires rabies vaccination can be made clinically by classifying the level of rabies exposure, which is divided into primary exposure, secondary exposure and tertiary exposure. The rabies vaccine is generally required for secondary and tertiary exposures.1. Primary exposure: Patients who usually touch or feed their pets, or whose skin is intact after being bitten or licked, and whose pets have been vaccinated, basically do not need rabies vaccination. However, those who cannot confirm whether the skin is intact should be treated with secondary exposure. 2. Secondary exposure: This refers to scratches or abrasions without bleeding, or bare skin that is lightly bitten but not bleeding. If it is difficult to distinguish with the naked eye, alcohol can be used to wipe the bite or scratch, and a tingling sensation mostly indicates that there is a break in the skin, which is a secondary exposure. A secondary exposure to rabies requires immediate wound irrigation, disinfection, and a trip to the hospital for rabies vaccination. However, if the wound is located on the head, or if there is serious suspicion that the bite was caused by a rabid animal, it should be treated in the same way as a tertiary exposure. 3. Tertiary exposure: mainly refers to three categories of people who have been bitten or scratched by an animal resulting in bleeding, the original broken part being licked by an animal, or the human mucous membrane being exposed to animal body fluids. A person with tertiary rabies exposure needs to immediately flush the wound with plenty of water and then disinfect it with iodophor, after which he or she should immediately go to the hospital and explain the bite to the doctor. In addition to the rabies vaccine, rabies grade III exposed persons need to be given rabies passive immunization preparations such as rabies immunoglobulin and anti-rabies serum.