Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoid drugs can be used to relieve symptoms in patients with acute gout attacks during chemotherapy. 1. Colchicine; small doses of colchicine can rapidly relieve joint pain, joint swelling and other symptoms caused by gout, but the contraindications of colchicine include hypoproliferative myelopathy and hepatic and renal insufficiency, therefore, patients with hypoproliferative myelopathy or hepatic and renal insufficiency cannot use colchicine for chemotherapy. 2. Non-steroidal anti-inflammatory drugs: non-steroidal anti-inflammatory drugs such as etoricoxib and diclofenac can provide analgesic and anti-inflammatory effects, and can also rapidly relieve the symptoms of patients with acute attacks of gout, but the use of this type of drug should be wary of gastrointestinal risks, and should be excluded from the contraindications to the use of drugs. 3. Glucocorticosteroids: For patients who are not well treated with colchicine and NSAIDs or who have contraindications to the use of these two types of drugs, glucocorticosteroids such as prednisone and methylprednisolone can be used, and attention should be paid to the adverse effects of the drugs, such as hyperglycemia and hyperlipidemia, during the treatment period. If gout attack occurs during chemotherapy, it is recommended to go to the rheumatology and immunology department of regular hospitals and other related departments for detailed consultation, and follow the doctor’s instructions to use medication.