First of all, 48 days of negative HIV is not a complete exclusion of AIDS, and high-risk individuals need to be retested after 3 months of infection in order to completely exclude it. Secondly, symptoms are not necessarily caused by AIDS, so it is not necessary to be too anxious. The window period of AIDS in 2 weeks to 3 months, so the AIDS risk 48 days after the negative test can only be used as a preliminary screening, and can not determine the existence of infection, high-risk 3 months after the retest if negative, can basically rule out infection. Early symptoms of AIDS are not specific, can be manifested as fever, muscle pain, joint pain, etc., the common cold will also appear this kind of symptom, so the symptom judgment is not accurate. To summarize, a 48-day negative HIV test cannot completely rule out HIV infection, and a repeat test is needed to make a diagnosis. Early symptoms of HIV are similar to those of a cold, so similar symptoms can be caused by a cold or other reasons, not necessarily HIV, so we suggest that you do not need to be too anxious and follow the doctor’s instructions for regular checkups. To minimize the risk of HIV infection, treatment should be given within 72 hours of exposure to HIV.