Pravastatin and Rosuvastatin Calcium Tablets are usually not taken at the same time, both belong to the statin class of drugs, and taking them at the same time may lead to aggravation of the adverse reactions, resulting in adverse consequences. 1. Pravastatin belongs to 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, which can reduce the content of cholesterol in serum and improve the serum lipid profile after use. It is mainly used in the treatment of hyperlipidemia, familial hypercholesterolemia and other diseases. Usually the drug may cause skin rashes, diarrhea and stomach upset after taking it. It is contraindicated for those who are allergic to the components of the drug. In the course of taking the drug, it is necessary to monitor aminotransferases, serum lipids, liver and kidney functions. Pregnant and lactating women should use the drug under medical supervision. 2. Rosuvastatin Calcium Tablet is a selective and competitive HMG-CoA reductase inhibitor, which can enhance the uptake and catabolism of LDL and inhibit the synthesis of cholesterol in the liver. It is mainly used for the treatment of mixed dyslipidemia and primary hypercholesterolemia. The drug may cause dizziness, nausea and other discomforts. The drug is contraindicated in people who are allergic to the components of the drug and in people with severe renal impairment. Meanwhile, liver and kidney functions should be monitored while taking the drug, and pregnant women and children should use the drug under the guidance of a doctor. 3. To summarize, pravastatin and Rosuvastatin Calcium Tablets belong to lipid-lowering drugs, and taking them at the same time may lead to a decrease in serum lipid levels, so they cannot be taken at the same time. All of the above medications should be used under the guidance of a doctor, avoid self-medication to avoid adverse consequences.