”Schizophrenia is a common psychiatric disorder whose cause is not fully understood. The main symptoms are disturbances in thinking, perception, emotion, and behavior. In general, there is no impairment of consciousness or intelligence. If not effectively treated, it will lead to impairment of the entire mental activity, including the degradation of social functions. This results in a mental and economic burden on the family and society. There are strict diagnostic criteria for the diagnosis of “schizophrenia” (CCMD-3 and DSM-IV). Before making a diagnosis, physicians must have a thorough and reliable understanding of the patient’s medical history, including pre-morbid psycho-social factors, the impact of adverse life events on the patient, and the possibility of physical illness triggering mental disorders and the existence of a family history. Once the diagnosis is confirmed, pharmacological treatment should be taken and the whole process of active treatment, including pharmacological-psychological-rehabilitation treatment, should be carried out as early as possible. At the same time, follow-up visits should be conducted to understand the changes of the disease and adjust the treatment plan in time. The key to treatment is that the doctor should choose the most appropriate medication according to the condition. It is important to control the main symptoms, improve the efficacy of treatment, strive for the best prognosis, and prepare patients to return to society and resume social functions. Strict prevention of adverse drug reactions is the principle and goal of treatment.