Long-term blockage of the nose may be due to nasal septum deviation, nasal hemangioma, allergic rhinitis, etc. Surgery and medication should be given according to the specific cause. 1. Deviated nasal septum: the structure of nasal septum is deviated to one side, which leads to long-term blockage of the nose, you can consider surgery, such as septoplasty, nasal septum correction and other treatments to unclog the nasal passage. 2. Nasal hemangioma: the nasal cavity has hemangioma blocking the nostrils causing long-term blockage of ventilation, you can endoscopic local injection of sclerosing agent, surgical resection of hemangioma, or through interventional therapy, to restore the normal ventilation of the nasal cavity. 3. Allergic rhinitis: physiological sea salt water can be given to rinse the nasal cavity to help nasal secretion discharge, oral cetirizine, loratadine, montelukast sodium and other medications, the nose, local application of budesonide nasal spray nasal spray, to improve the mucosal edema of the nasal cavity, to alleviate the nasal congestion and lack of ventilation. Long-term blockage of the nose, there may be other reasons, it is recommended to seek medical advice to identify the cause of the disease, under the guidance of the doctor to standardize the use of drugs and treatment.