Infection with the monkeypox virus may lead to death in patients. Monkeypox is a self-limiting disease that can lead to symptoms such as fever, headache, rash, pustules and swollen lymph nodes. In general, most patients can recover on their own. However, some patients with severe disease may die due to weakness. Once diagnosed with this disease. It should be isolated properly to avoid infecting relatives or causing widespread spread. For patients, they should be treated early, which can effectively shorten the course of the disease and relieve the uncomfortable symptoms. In some severe cases, failure to intervene in time may result in collapse and death. Although the disease is self-limiting, there is still a risk of death, and patients are advised to pay attention and seek timely medical treatment to avoid adverse consequences.