Patient: Description of condition (onset, main symptoms, hospital visited, etc.): My mother had a left mastectomy on July 30. Frozen section report: “Left” breast ductal high-grade intraepithelial neoplasia, localized intra-ductal carcinoma, size 1cm x 1cm. 2. Pathological diagnosis: “Left” breast ductal high-grade intra-epithelial neoplasia, localized intra-ductal carcinoma. The remaining tissue lesions were the same as above. 3. pathological diagnosis: left breast modified radical specimen: no tumor tissue remains under the original incision, paracancerous breast showed adenopathy image, nipple (-) axillary lymph nodes (-) 0/17 4. immunohistochemical marker results: ER (+), PR (++), intraductal tumor cells cerbB-2 (++) Now just postoperative hanging some anti-inflammatory oral letrozole tablets (domestic), once a day I do not know whether my Does my mother need chemotherapy? Is there any risk without chemotherapy? Do I need to go to Fudan for fish test? Thank you, doctor! Pan Ziqiang, Department of Radiation Therapy, Cancer Hospital of Fudan University: Your mother’s disease stage is T1N0M0, low risk, no need for chemotherapy, oral endocrine drugs can be taken, depending on whether she is menopausal or not.