Sudden deterioration of vision with keratoplasty lenses may be related to keratoplasty lens prescription mismatch, corneal inflammation, and fundus retinopathy. 1. Mismatch of keratoplasty lenses: If the keratoplasty lenses are mismatched and do not meet the needs of the eyes, vision loss and blurred vision may occur. To deal with this situation, you need to re-do the vision test, and then reconfigure the corneal reshaping lens according to the test result. 2. Corneal inflammation: Improper use of corneal reshaping lenses and patients’ lack of attention to hygiene can lead to corneal inflammation, which may result in eye pain, photophobia, tearing, blepharospasm, and other symptoms, and may be accompanied by different degrees of vision loss, blurred vision, and poor visual acuity. 3. Retinopathy of the fundus: For more serious myopia, retinopathy of the fundus may occur, in this case, simply wearing keratoplasty may not be able to improve the problem of vision loss, and it is necessary to treat according to the specific conditions of the fundus lesion. If you find that your vision deteriorates after wearing keratoplasty lenses, you need to consult a doctor in time and analyze the cause through a series of examinations, and then make timely adjustments to avoid causing more serious symptoms.